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Article

In-vitro, SDH5-dependent flavinylation of immobilized human respiratory complex II flavoprotein.

Archives of biochemistry and biophysics - 15 Aug 2016

Zafreen Lala, Walker-Kopp Nancy, Huang Li-Shar, Berry Edward

Abstract excerpt

Mitochondrial Complex II (Succinate: ubiquinone oxidoreductase) has a covalently bound FAD cofactor in its largest subunit (SDHA), which accepts electrons from oxidation of succinate during catalysis. The mechanism of flavin attachment, and factors involved, have not been fully elucidated. The recent report of an assembly factor SDH5 (SDHAF2, SDHE) required for flavinylation (Hao et al., 2009 Science 325,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27296776
DOI: 10.1016/j.abb.2016.06.006

Genes

SDHA
SDHAF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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