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Article

Structural and biochemical analyses reveal insights into covalent flavinylation of the Escherichia coli Complex II homolog quinol:fumarate reductase.

The Journal of biological chemistry - 4 Aug 2017

Starbird C A, Maklashina Elena, Sharma Pankaj, Qualls-Histed Susan, Cecchini Gary, Iverson T M

Abstract excerpt

The Escherichia coli Complex II homolog quinol:fumarate reductase (QFR, FrdABCD) catalyzes the interconversion of fumarate and succinate at a covalently attached FAD within the FrdA subunit. The SdhE assembly factor enhances covalent flavinylation of Complex II homologs, but the mechanisms underlying the covalent attachment of FAD remain to be fully elucidated. Here, we explored the mechanisms of covalent...

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Identifiers

PMID: 28615448
DOI: 10.1074/jbc.M117.795120
PMCID: PMC5546032

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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