Article
PDCD1 PD-1.3 polymorphism and allergic bronchial asthma in Russian and Buryat patients.
The Journal of asthma : official journal of the Association for the Care of Asthma - 2 Jan 2017
Dmitrieva-Zdorova Elena V, Gabaeva Marina V, Seregin Yuri A, Bodoev Nikolay V, Voronko Olga E
Abstract excerpt
OBJECTIVE: The programmed death-1 receptor, PD-1, is a negative regulator of T-cell activation. The PD-1.3 polymorphism of the PD-1 gene (PDCD1) has been previously shown to be associated with several autoimmune and inflammatory disorders including systemic lupus erythematosus and multiple sclerosis. We examined for the first time PD-1.3 association with another inflammatory disease with strong immune component,...
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