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Article

Analysis of polymorphisms in T(H)2-associated genes in Russian patients with atopic bronchial asthma.

Journal of investigational allergology & clinical immunology - 1 Jan 2012

Dmitrieva-Zdorova E V, Voronko O E, Latysheva E A, Storozhakov G I, Archakov A I

Abstract excerpt

BACKGROUND: Bronchial asthma is a chronic respiratory disorder characterized by airway inflammation, airway hyperresponsiveness, and periodic reversible airway obstruction. Subtype 2 helperT cell (T(H)2) cytokines play an important role in the development of allergic airway inflammation in patients with bronchial asthma. OBJECTIVE: To investigate whether the single-nucleotide polymorphisms (SNPs) Ile75Val and...

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PMID: 22533235

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