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Article

Expression of inflammation-related genes in aldosterone-producing adenomas with KCNJ5 mutation.

Biochemical and biophysical research communications - 5 Aug 2016

Murakami Masanori, Yoshimoto Takanobu, Nakano Yujiro, Tsuchiya Kyoichiro, Minami Isao, Bouchi Ryotaro, Fujii Yasuhisa, Nakabayashi Kazuhiko, Hashimoto Koshi, Hata Ken-Ichiro, Kihara Kazunori, Ogawa Yoshihiro

Abstract excerpt

BACKGROUND: The adrenocortical cells have been shown to produce various inflammatory cytokines such as TNFα and IL-6, which could modulate steroidogenesis. However, the role of inflammatory cytokines in aldosterone-producing adenomas (APAs) is not fully understood. In the present study, we examined the relationships between mRNA expression levels of the inflammation-related genes and somatic mutations in APA...

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Share to Adrenal Cortex Neoplasms
Share to Adrenocortical Adenoma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Aldosterone

Share to G Protein-Coupled Inwardly-Rectifying Potassium Channels

Share to Inflammation Mediators

Share to NF-kappa B p50 Subunit

Share to RNA, Neoplasm

Share to Steroid 11-beta-Hydroxylase

Source

Identifiers

PMID: 27282482
DOI: 10.1016/j.bbrc.2016.06.007

Genes

KCNJ5
NFKB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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