Article
Single-Nucleotide Polymorphisms and Markers of Oxidative Stress in Healthy Women.
PloS one - 1 Jan 2016
Minlikeeva Albina N, Browne Richard W, Ochs-Balcom Heather M, Marian Catalin, Shields Peter G, Trevisan Maurizio, Krishnan Shiva, Modali Ramakrishna, Seddon Michael, Lehman Teresa, Freudenheim Jo L
Abstract excerpt
PURPOSE: There is accumulating evidence that oxidative stress is an important contributor to carcinogenesis. We hypothesized that genetic variation in genes involved in maintaining antioxidant/oxidant balance would be associated with overall oxidative stress. METHODS: We examined associations between single nucleotide polymorphisms (SNPs) in MnSOD, GSTP1, GSTM1, GPX1, GPX3, and CAT genes and thiobarbituric...
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