Prognostic impact of bone marrow fibrosis in primary myelofibrosis. A study of the AGIMM group on 490 patients.

doi:10.1002/ajh.24442

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Article

Prognostic impact of bone marrow fibrosis in primary myelofibrosis. A study of the AGIMM group on 490 patients.

American journal of hematology - 1 Sept 2016

Guglielmelli Paola, Rotunno Giada, Pacilli Annalisa, Rumi Elisa, Rosti Vittorio, Delaini Federica, Maffioli Margherita, Fanelli Tiziana, Pancrazzi Alessandro, Pieri Lisa, Fjerza Rajmonda, Pietra Daniela, Cilloni Daniela, Sant'Antonio Emanuela, Salmoiraghi Silvia, Passamonti Francesco, Rambaldi Alessandro, Barosi Giovanni, Barbui Tiziano, Cazzola Mario, Vannucchi Alessandro M

Abstract excerpt

The prognostic significance of bone marrow (BM) fibrosis grade in patients with primary myelofibrosis (PMF) is still debated. A fibrosis grade greater than 1 was shown to associate with higher risk of death, and addition of fibrosis grade to IPSS score resulted in a more accurate prediction of survival. The aim of this study was to analyze the prognostic impact of BM fibrosis in 490 patients with PMF, evaluated...

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PMID: 27264006
DOI: 10.1002/ajh.24442

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ASXL1

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