Article
Presentation and outcome of patients with 2016 WHO diagnosis of prefibrotic and overt primary myelofibrosis.
Blood - 15 Jun 2017
Guglielmelli Paola, Pacilli Annalisa, Rotunno Giada, Rumi Elisa, Rosti Vittorio, Delaini Federica, Maffioli Margherita, Fanelli Tiziana, Pancrazzi Alessandro, Pietra Daniela, Salmoiraghi Silvia, Mannarelli Carmela, Franci Annalisa, Paoli Chiara, Rambaldi Alessandro, Passamonti Francesco, Barosi Giovanni, Barbui Tiziano, Cazzola Mario, Vannucchi Alessandro M
Abstract excerpt
The 2016 revision of the World Health Organization (WHO) classification of myeloproliferative neoplasms defines 2 stages of primary myelofibrosis (PMF): prefibrotic/early (pre-PMF) and overt fibrotic (overt PMF) phase. In this work, we studied the clinical and molecular features of patients belonging to these categories of PMF. The diagnosis of 661 PMF patients with a bone marrow biopsy at presentation was...
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