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Article

Combination of mouse models and genomewide association studies highlights novel genes associated with human kidney function.

Kidney international - 1 Oct 2016

Jing Jiaojiao, Pattaro Cristian, Hoppmann Anselm, Okada Yukinori, Fox Caroline S, Köttgen Anna

Abstract excerpt

Genomewide association studies have identified numerous chronic kidney disease-associated genetic variants, but often do not pinpoint causal genes. This limitation was addressed by combining Mouse Genome Informatics with human genomewide association studies of kidney function. Genes for which mouse models showed abnormal renal physiology, morphology, glomerular filtration rate (GFR), or urinary...

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PMID: 27263491
DOI: 10.1016/j.kint.2016.04.004

Genes

BMP4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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