Article
Principles of microRNA Regulation Revealed Through Modeling microRNA Expression Quantitative Trait Loci.
Genetics - 1 Aug 2016
Budach Stefan, Heinig Matthias, Marsico Annalisa
Abstract excerpt
Extensive work has been dedicated to study mechanisms of microRNA-mediated gene regulation. However, the transcriptional regulation of microRNAs themselves is far less well understood, due to difficulties determining the transcription start sites of transient primary transcripts. This challenge can be addressed using expression quantitative trait loci (eQTLs) whose regulatory effects represent a natural source of...
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