Article
dPORE-miRNA: polymorphic regulation of microRNA genes.
PloS one - 4 Feb 2011
Schmeier Sebastian, Schaefer Ulf, MacPherson Cameron R, Bajic Vladimir B
Abstract excerpt
BACKGROUND: MicroRNAs (miRNAs) are short non-coding RNA molecules that act as post-transcriptional regulators and affect the regulation of protein-coding genes. Mostly transcribed by PolII, miRNA genes are regulated at the transcriptional level similarly to protein-coding genes. In this study we focus on human miRNAs. These miRNAs are involved in a variety of pathways and can affect many diseases. Our interest is...
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