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Article

Identification and genotype phenotype correlation of novel mutations in SIX6 gene in primary open angle glaucoma.

Ophthalmic genetics - 1 Jun 2018

Mohanty Kuldeep, Dada Rima, Dada Tanuj

Abstract excerpt

BACKGROUND: Recently SIX1 and SIX6 genes have been associated with primary open angle glaucoma (POAG). This study was planned to do mutation screening in SIX1 and SIX6 genes in North Indian POAG patients and correlate with clinical phenotypes. MATERIALS AND METHODS: SIX1 and SIX6 genes were amplified by PCR and sequenced in 115 POAG cases and 105 controls. Four pathogenecity prediction tools (MutationTaster,...

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Source

Identifiers

PMID: 29405792
DOI: 10.1080/13816810.2018.1432062

Genes

SIX6
SIX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Identification and genotype phenotype correlation of novel mutations in SIX6 gene in primary open angle glaucoma.PMID 29405792Read ↗

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