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Article

Involvement of genetic variants associated with primary open-angle glaucoma in pathogenic mechanisms and family history of glaucoma.

American journal of ophthalmology - 1 Mar 2015

Mabuchi Fumihiko, Sakurada Yoichi, Kashiwagi Kenji, Yamagata Zentaro, Iijima Hiroyuki, Tsukahara Shigeo

Abstract excerpt

PURPOSE: To investigate the associations between the non-intraocular pressure (IOP)-related genetic variants (genetic variants associated with vulnerability of the optic nerve independent of IOP) and primary open-angle glaucoma (POAG), including normal-tension glaucoma (NTG) and high-tension glaucoma (HTG), and between the non-IOP-related genetic variants and a family history of glaucoma. DESIGN: Case-control...

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Source

Identifiers

PMID: 25461262
DOI: 10.1016/j.ajo.2014.11.023

Genes

ATOH7
ELOVL5
SIX1
SIX6
SRBD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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