Article
Short Telomere Length and Ischemic Heart Disease: Observational and Genetic Studies in 290 022 Individuals.
Clinical chemistry - 1 Aug 2016
Scheller Madrid Alexander, Rode Line, Nordestgaard Børge G, Bojesen Stig E
Abstract excerpt
BACKGROUND: Short telomeres are associated with aging and have been associated with a high risk of ischemic heart disease in observational studies; however, the latter association could be due to residual confounding and/or reverse causation. We wanted to test the hypothesis that short telomeres are associated with high risk of ischemic heart disease using a Mendelian randomization approach free of reverse...
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