Article
Association of MHC region SNPs with irritant susceptibility in healthcare workers.
Journal of immunotoxicology - 1 Sept 2016
Yucesoy Berran, Talzhanov Yerkebulan, Michael Barmada M, Johnson Victor J, Kashon Michael L, Baron Elma, Wilson Nevin W, Frye Bonnie, Wang Wei, Fluharty Kara, Gharib Rola, Meade Jean, Germolec Dori, Luster Michael I, Nedorost Susan
Abstract excerpt
Irritant contact dermatitis is the most common work-related skin disease, especially affecting workers in "wet-work" occupations. This study was conducted to investigate the association between single nucleotide polymorphisms (SNPs) within the major histocompatibility complex (MHC) and skin irritant response in a group of healthcare workers. 585 volunteer healthcare workers were genotyped for MHC SNPs and patch...
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