Article
[Recent progress in genetic background of chronic obstructive pulmonary disease (COPD)].
Nihon rinsho. Japanese journal of clinical medicine - 1 May 2016
Teramoto Shinji
Abstract excerpt
A genetic contribution to develop chronic obstructive pulmonary disease(COPD) is estimated. However, candidate gene studies on COPD and related phenotypes have not been well replicated. Research on the genetic pathologic background of COPD using genome-wide association studies (GWASs) has progressed in recent years. The novel candidate genes including CHRNA3/5 (cholinergic nicotine receptor alpha 3/5), IREB2...
Topics
- Carrier Proteins
- Disease Progression
- GTPase-Activating Proteins
- Genetic Predisposition to Disease
- Genome-Wide Association Study
- Humans
- Iron Regulatory Protein 2
- Membrane Glycoproteins
- Nerve Tissue Proteins
- Polymorphism, Genetic