Article
What do polymorphisms tell us about the mechanisms of COPD?
Clinical science (London, England : 1979) - 15 Dec 2017
Li Yan, Cho Michael H, Zhou Xiaobo
Abstract excerpt
COPD (chronic obstructive pulmonary disease) is characterized by irreversible lung airflow obstruction. Cigarette smoke is the major risk factor for COPD development. However, only a minority number of smokers develop COPD, and there are substantial variations in lung function among smokers, suggesting that genetic determinants in COPD susceptibility. During the past decade, genome-wide association studies and...
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