Article
Genetics of COPD.
Allergology international : official journal of the Japanese Society of Allergology - 1 Sept 2011
Nakamura Hidetoshi
Abstract excerpt
Previous family studies suggested that genetic variation contributes to COPD susceptibility. The only gene proven to influence COPD susceptibility is SERPINA1, encoding α1-antitrypsin. Most studies on COPD candidate genes except SERPINA1, have not been consistently replicated. However, longitudinal studies of decline in lung function, meta-analyses of candidate gene studies, and family-based linkage analyses...
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