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Article

Hippo pathway effectors YAP, TAZ and TEAD are associated with EMT master regulators ZEB, Snail and with aggressive phenotype in phyllodes breast tumors.

Pathology, research and practice - 1 Oct 2024

Akrida Ioanna, Makrygianni Maria, Nikou Sofia, Mulita Francesk, Bravou Vasiliki, Papadaki Helen

Abstract excerpt

BACKGROUND: Phyllodes tumors (PTs) of the breast are uncommon fibroepithelial neoplasms that tend to recur locally and may have metastatic potential. Their pathogenesis is poorly understood. Hippo signaling pathway plays an essential role in organ size control, tumor suppression, tissue regeneration and stem cell self-renewal. Hippo signaling dysfunction has been implicated in cancer. Recent evidence suggests...

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Share to Adaptor Proteins, Signal Transducing
Share to Epithelial-Mesenchymal Transition

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Intracellular Signaling Peptides and Proteins

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Share to Snail Family Transcription Factors

Share to YAP-Signaling Proteins

Share to Zinc Finger E-box-Binding Homeobox 1

Source

Identifiers

PMID: 39153238
DOI: 10.1016/j.prp.2024.155551

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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Hippo pathway effectors YAP, TAZ and TEAD are associated with EMT master regulators ZEB, Snail and with aggressive phenotype in phyllodes breast tumors.PMID 39153238Read ↗

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