Article
Molecular analysis of mucinous nonneoplastic cyst of the pancreas.
Human pathology - 1 Sept 2016
Zhu Bing, Finkelstein Sydney D, Feng Gong, Keswani Rajesh N, Lin Xiaoqi
Abstract excerpt
Although a mucinous nonneoplastic cyst (MNNC) of the pancreas is defined as a benign nonneoplastic lesion with no malignant potential, its histogenesis and etiology are still uncertain. To explore the origin and development of MNNC, we searched for neoplasia-associated mutational change in oncogene and tumor suppressor genes. Specifically, we analyzed KRAS oncogene mutations by polymerase chain reaction/dideoxy...
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