Article
Next-generation sequencing of residual cytologic fixative preserved DNA from pancreatic lesions: A pilot study.
Cancer cytopathology - 1 Nov 2020
Fulmer Clifton G, Park Kyung, Dilcher Thomas, Ho Mai, Mirabelli Susanna, Alperstein Susan, Hissong Erika M, Pittman Meredith, Siddiqui Momin, Heymann Jonas J, Yantiss Rhonda K, Borczuk Alain C, Fernandes Helen, Sigel Carlie, Song Wei, Mosquera Juan Miguel, Rao Rema
Abstract excerpt
BACKGROUND: Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) is a sensitive and specific tool in the risk stratification of pancreatic lesions, including cysts. The sensitivity and specificity of EUS-FNA has been shown to improve when cytology is combined with next-generation sequencing (NGS). Ideally, fresh cyst fluid is used for NGS. In this pilot study, we explore the possibility of sequencing DNA...
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