Article
Global assessment of imprinted gene expression in the bovine conceptus by next generation sequencing.
Epigenetics - 2 Jul 2016
Chen Zhiyuan, Hagen Darren E, Wang Juanbin, Elsik Christine G, Ji Tieming, Siqueira Luiz G, Hansen Peter J, Rivera Rocío M
Abstract excerpt
Genomic imprinting is an epigenetic mechanism that leads to parental-allele-specific gene expression. Approximately 150 imprinted genes have been identified in humans and mice but less than 30 have been described as imprinted in cattle. For the purpose of de novo identification of imprinted genes in bovine, we determined global monoallelic gene expression in brain, skeletal muscle, liver, kidney and placenta of...
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