Article
ZFAT (isoform-specific) and its antisense RNA 1 (ZFAT-AS1) are two allele-specific monoallelically expressed genes in cattle.
Animal genetics - 1 Dec 2024
Zhang Yinjiao, Zheng Yunchang, Yu Wenli, Yang Lidan, Zhang Cui, Li Shujing, Li Shijie
Abstract excerpt
In mammals, imprinted genes are characterised by a monoallelic expression, which is based on parental origin and is essential for both foetal and placental development. The ZFAT gene encodes a transcriptional factor, and its non-coding antisense RNA, ZFAT-AS1, overlaps with the ZFAT locus. Both ZFAT and ZFAT-AS1 are maternally imprinted in human placentas. In bovines, the imprinting status of the ZFAT and...
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