Article
TREM-1low is a novel characteristic for tumor-associated macrophages in lung cancer.
Oncotarget - 28 Jun 2016
Zhang Guangbo, Liu Hongmei, Huang Jian, Chen Siwen, Pan Xudong, Huang Haitao, Wang Ling
Abstract excerpt
OBJECTIVE: To explore the expression feature and biological functions of TREM-1 on tumor-associated macrophages (TAMs) in lung cancer. RESULTS: The levels of TREM-1 on tissue-infiltrating monocytes/macrophage from tumor nest were significantly lower than those from nonturmor tissue or peripheral blood samples. Clinical analysis indicated that the levels of TREM-1-related TAMs were significantly decreased during...
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