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Article

Systematic Pan-Cancer Analysis Identifies TREM2 as an Immunological and Prognostic Biomarker.

Frontiers in immunology - 1 Jan 2021

Cheng Xin, Wang Xiaowei, Nie Kechao, Cheng Lin, Zhang Zheyu, Hu Yang, Peng Weijun

Abstract excerpt

Triggering receptor expressed on myeloid cells-2 (TREM2) is a transmembrane receptor of the immunoglobulin superfamily and a crucial signaling hub for multiple pathological pathways that mediate immunity. Although increasing evidence supports a vital role for TREM2 in tumorigenesis of some cancers, no systematic pan-cancer analysis of TREM2 is available. Thus, we aimed to explore the prognostic value, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33679809
DOI: 10.3389/fimmu.2021.646523
PMCID: PMC7925850

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