Article
Urinary soluble CD163 level reflects glomerular inflammation in human lupus nephritis.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Dec 2016
Endo Nobuhide, Tsuboi Naotake, Furuhashi Kazuhiro, Shi Yiqin, Du Qiuna, Abe Tomoko, Hori Mayuko, Imaizumi Takahiro, Kim Hangsoo, Katsuno Takayuki, Ozaki Takenori, Kosugi Tomoki, Matsuo Seiichi, Maruyama Shoichi
Abstract excerpt
BACKGROUND: In addition to classically activated macrophages that have effector roles in tissue injury, alternatively activated M2 macrophages are involved in the resolution of inflammation in animal models of kidney disease. To clarify the clinical relevance of macrophage phenotypes in human glomerular diseases, we evaluated the renal accumulation of macrophages and plasma and urine levels of CD163, an M2...
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