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M1 and M2 Macrophage Polarization Correlates with Activity and Chronicity Indices in Lupus Nephritis

4 Jan 2025

Abstract excerpt

Background: Lupus nephritis (LN) is a severe manifestation of systemic lupus erythematosus (SLE), characterized by inflammation and immune dysregulation in the kidneys. The role of macrophage polarization in LN progression remains underexplored. Objective: This study examined the association between tubulointerstitial M1/M2 macrophage subpopulations and LN indices of activity and chronicity. Materials and...

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PMID: 39859995
DOI: 10.3390/life15010055

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