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Article

The macrophage activation marker soluble CD163 is elevated and associated with liver disease phenotype in patients with Wilson's disease.

Orphanet journal of rare diseases - 2 Jul 2020

Glavind Emilie, Gotthardt Daniel N, Pfeiffenberger Jan, Sandahl Thomas Damgaard, Bashlekova Teodora, Willemoe Gro Linno, Hasselby Jane Preuss, Weiss Karl Heinz, Møller Holger Jon, Vilstrup Hendrik, Lee William M, Schilsky Michael L, Ott Peter, Grønbæk Henning

Abstract excerpt

BACKGROUND: Macrophages play a significant role in liver disease development and progression. The macrophage activation marker soluble (s)CD163 is associated with severity and prognosis in a number of different acute and chronic liver diseases but has been only sparsely examined in Wilson's disease (WD). We investigated sCD163 levels in patients with acute and chronic WD and hypothesized associations with liver...

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Share to Antigens, CD
Share to Antigens, Differentiation, Myelomonocytic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32615997
DOI: 10.1186/s13023-020-01452-2
PMCID: PMC7331244

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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