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Article

Genomic profiling and directed ex vivo drug analysis of an unclassifiable myelodysplastic/myeloproliferative neoplasm progressing into acute myeloid leukemia.

Genes, chromosomes & cancer - 1 Nov 2016

Hyrenius-Wittsten Axel, Sturesson Helena, Bidgoli Mahtab, Jonson Tord, Ehinger Mats, Lilljebjörn Henrik, Scheding Stefan, Andersson Anna K

Abstract excerpt

Myelodysplastic/myeloproliferative neoplasms, unclassifiable (MDS/MPN-U) are rare genetically heterogeneous hematologic diseases associated with older age and a poor prognosis. If the disease progresses into acute myeloid leukemia (AML), it is often refractory to treatment. To gain insight into genetic alterations associated with disease progression, whole exome sequencing and single nucleotide polymorphism...

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PMID: 27240832
DOI: 10.1002/gcc.22384

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NRAS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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