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Article

Folate-/FAD-dependent tRNA methyltransferase from Thermus thermophilus regulates other modifications in tRNA at low temperatures.

Genes to cells : devoted to molecular & cellular mechanisms - 1 Jul 2016

Yamagami Ryota, Tomikawa Chie, Shigi Naoki, Kazayama Ai, Asai Shin-Ichi, Takuma Hiroyuki, Hirata Akira, Fourmy Dominique, Asahara Haruichi, Watanabe Kimitsuna, Yoshizawa Satoko, Hori Hiroyuki

Abstract excerpt

TrmFO is a N(5) , N(10) -methylenetetrahydrofolate (CH2 THF)-/FAD-dependent tRNA methyltransferase, which synthesizes 5-methyluridine at position 54 (m(5) U54) in tRNA. Thermus thermophilus is an extreme-thermophilic eubacterium, which grows in a wide range of temperatures (50-83 °C). In T. thermophilus, modified nucleosides in tRNA and modification enzymes form a network, in which one modification regulates the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 27238446
DOI: 10.1111/gtc.12376

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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