Article
Similar frequencies, phenotype and activation status of intrahepatic NK cells in chronic HBV patients after long-term treatment with tenofovir disoproxil fumarate (TDF).
Antiviral research - 1 Aug 2016
Tjwa Eric T T L, Zoutendijk Roeland, van Oord Gertine W, Boeijen Lauke L, Reijnders Jurrien G P, van Campenhout Margo J H, de Knegt Robert J, Janssen Harry L A, Woltman Andrea M, Boonstra Andre
Abstract excerpt
BACKGROUND: Currently, much effort is directed at further improving treatment for chronic hepatitis B patients by assessing the effect of immunomodulatory agents during therapy with nucleotide analogues (NUC). Although there are some reports on the effect of NUC therapy on peripheral natural killer (NK) cells, no studies investigated the long-term effects of NUC treatment on intrahepatic NK cells of chronic HBV...
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