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Article

Activation of Cold-Sensitive Channels TRPM8 and TRPA1 Inhibits the Proliferative Airway Smooth Muscle Cell Phenotype.

Lung - 1 Aug 2016

Zhang Lin, An Xiaofei, Wang Qiuyu, He Ming

Abstract excerpt

PURPOSE: Airway smooth muscle cell (ASMC) phenotypic modulation is one of the key factors contributing to asthma. Temperature changes may induce asthma, and these changes are known to be related to the temperature-sensitive transient receptor potential channels (TS-TRPs). The present study was designed to investigate the cellular functions of cold-sensitive channels, TRPM8 and TRPA1, in the phenotypic modulation...

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Source

Identifiers

PMID: 27236325
DOI: 10.1007/s00408-016-9901-4

Genes

TRPA1
TRPM8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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