Article
Nuclear factor-κB mediates the phenotype switching of airway smooth muscle cells in a murine asthma model.
International journal of clinical and experimental pathology - 1 Jan 2015
Qiu Chen, Zhang Jian, Su Meiping, Fan Xiujun
Abstract excerpt
Airway smooth muscle cells (ASMCs) phenotype modulation, characterized by reversible switching between contractile and proliferative phenotypes, is considered to contribute to airway proliferative diseases such as allergic asthma. Nuclear Factor-κB (NF-κB) has been reported as a key regulator for the occurrence and development of asthma. However, little is known regarding its role in ASM cell phenotypic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
