Article
Association Interleukin-4 and Interleukin-4 Receptor Gene Polymorphism and Acute Rejection and Graft Dysfunction After Kidney Transplantation.
Transplantation proceedings - 1 Apr 2016
Lee H J, Kim T H, Kang S W, Kim Y H, Kim S K, Chung J-H, Kim Y G, Moon J Y, Lee S H, Ihm C G, Lee T W, Jeong K H
Abstract excerpt
BACKGROUND: Cytokine genotypes have previously been studied in patients undergoing solid organ transplantation; certain polymorphisms have been implicated in the development of acute rejection (AR) and graft dysfunction (GD). Allograft outcomes determined, in part, by alloimmune responses is mainly mediated by T-cell responses, activated and driven by cytokines. Interleukin-4 (IL-4) is one such cytokine, which...
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