Article
Donor cytokine genotype influences the development of acute rejection after renal transplantation.
Transplantation - 15 Feb 2001
Marshall S E, McLaren A J, McKinney E F, Bird T G, Haldar N A, Bunce M, Morris P J, Welsh K I
Abstract excerpt
BACKGROUND: Acute allograft rejection remains an important cause of morbidity after kidney transplantation, and has been shown to be a crucial determinant of long-term graft function. Although rejection is mediated by recipient lymphocytes, both donor and recipient factors contribute to the local environment that influences the nature, severity, and duration of the rejection response. Cytokines are a major...
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