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Article

A study of the impact of cytokine gene polymorphism in acute rejection of renal transplant recipients.

Molecular biology reports - 1 Jan 2012

Karimi Mohammad Hossein, Daneshmandi Saeed, Pourfathollah Ali Akbar, Geramizadeh Bita, Yaghobi Ramin, Rais-Jalali Ghanbar Ali, Roozbeh Jamshid, Bolandparvaz Shahram

Abstract excerpt

Acute rejection is a common phenomenon in transplantation. Inflammatory and anti-inflammatory mediators affect the graft microenvironment. Th1 responses cause acute rejection while Th2 immune responses help the survival of the graft. In this study, we evaluated gene polymorphisms of IL-6 G-174C, TGF-β T+869C, IL-4 C-590T, and IFN-γ T+874A cytokines in renal transplant patients. ARMS-PCR method was used to...

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Identifiers

PMID: 21562768
DOI: 10.1007/s11033-011-0765-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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