Article

SMAD4 haploinsufficiency in small intestinal neuroendocrine tumors

2020-12-14

Abstract excerpt

<title>Abstract</title> <p><bold>Background </bold>Patients with small intestinal neuroendocrine tumors (SINETs) frequently present with lymph node and liver metastases at the time of diagnosis, but the molecular changes that lead to the progression of these tumors are largely unknown. Sequencing studies have only identified recurrent point mutations at low frequencies with <italic>CDKN1B </italic>being the most...

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Literature Corpus work: dde18c35-b779-5e66-9498-e3f9e4112837
DOI: 10.21203/rs.3.rs-39799/v2

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