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Article

TCEB3C a putative tumor suppressor gene of small intestinal neuroendocrine tumors

18 Dec 2013

Abstract excerpt

Small intestinal neuroendocrine tumors (SI-NETs), formerly known as midgut carcinoids, are rare and slow-growing neoplasms. Frequent loss of one copy of chromosome 18 in primary tumors and metastases has been observed. The aim of the study was to investigate a possible role of TCEB3C (Elongin A3), currently the only imprinted gene on chromosome 18, as a tumor suppressor gene in SI-NETs, and whether its expression...

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PMID: 24351681
DOI: 10.1530/erc-13-0419

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