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Colorectal adenoma and cancer detection based on altered methylation pattern of SFRP1, SFRP2, SDC2 , and PRIMA1 in plasma samples

28 Jul 2017

Abstract excerpt

Aberrant methylation is one of the most frequent epigenetic alterations that can contribute to tumor formation. Cell-free DNA can originate from tumor tissue; therefore, the evaluation of methylation markers in cell-free DNA can be a promising method for cancer screening. Our aim was to develop a panel of biomarkers with altered methylation along the colorectal adenoma-carcinoma sequence in both colonic tissue...

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Share to Colorectal Cancer Screening and Detection
Share to Epigenetics and DNA Methylation
Share to Genetic factors in colorectal cancer

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PMID: 28753106
DOI: 10.1080/15592294.2017.1356957

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