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Article

miRNA-dependent target regulation: functional characterization of single-nucleotide polymorphisms identified in genome-wide association studies of Alzheimer's disease.

Alzheimer's research & therapy - 24 May 2016

Delay Charlotte, Grenier-Boley Benjamin, Amouyel Philippe, Dumont Julie, Lambert Jean-Charles

Abstract excerpt

BACKGROUND: A growing body of evidence suggests that microRNAs (miRNAs) are involved in Alzheimer's disease (AD) and that some disease-associated genetic variants are located within miRNA binding sites. In the present study, we sought to characterize functional polymorphisms in miRNA target sites within the loci defined in earlier genome-wide association studies (GWAS). The main objectives of this study were to...

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PMID: 27215977
DOI: 10.1186/s13195-016-0186-x
PMCID: PMC4878064

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FERMT2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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