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Article

Genome-wide identification of microRNA-related variants associated with risk of Alzheimer's disease.

Scientific reports - 22 Jun 2016

Ghanbari Mohsen, Ikram M Arfan, de Looper Hans W J, Hofman Albert, Erkeland Stefan J, Franco Oscar H, Dehghan Abbas

Abstract excerpt

MicroRNAs (miRNAs) serve as key post-transcriptional regulators of gene expression. Genetic variation in miRNAs and miRNA-binding sites may affect miRNA function and contribute to disease risk. Here, we investigated the extent to which variants within miRNA-related sequences could constitute a part of the functional variants involved in developing Alzheimer's disease (AD), using the largest available genome-wide...

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PMID: 27328823
DOI: 10.1038/srep28387
PMCID: PMC4916596

Genes

SORL1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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