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Article

Comparison of next generation sequencing, SNaPshot assay and real-time polymerase chain reaction for lung adenocarcinoma EGFR mutation assessment.

BMC pulmonary medicine - 23 May 2016

Cernomaz Andrei-Tudor, Macovei Ina Iuliana, Pavel Ionut, Grigoriu Carmen, Marinca Mihai, Baty Florent, Peter Simona, Zonda Radu, Brutsche Martin, Grigoriu Bogdan- Dragos

Abstract excerpt

BACKGROUND: The epidermal growth factor receptor (EGFR) mutation status assessment has become increasingly important given the significant impact of tyrosine kinase inhibitors in lung cancer management. Our aim was to compare real life operational characteristics for three EGFR mutation assays - two targeted approaches and a next generation sequencing (NGS) technique. METHODS: EGFR mutation status was assessed...

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Identifiers

PMID: 27215400
DOI: 10.1186/s12890-016-0250-0
PMCID: PMC4877937

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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