Article
Brief Report: HLA-DRB1, DQA1, and DQB1 in Juvenile-Onset Systemic Sclerosis.
Arthritis & rheumatology (Hoboken, N.J.) - 1 Nov 2016
Stevens Anne M, Kanaan Sami B, Torok Kathryn S, Medsger Thomas A, Mayes Maureen D, Reveille John D, Klein-Gitelman Marisa, Reed Ann M, Lee Tzielan, Li Suzanne C, Henstorf Gretchen, Luu Christine, Aydelotte Tessa, Nelson J Lee
Abstract excerpt
OBJECTIVE: Systemic sclerosis (SSc) is a rare disease that is particularly uncommon in children. Specific HLA alleles have been associated with SSc in adults. This study was undertaken to investigate HLA class II alleles in juvenile-onset SSc. METHODS: DRB1, DQA1, and DQB1 alleles were determined by DNA-based HLA typing. Analyses were conducted comparing Caucasian patients with juvenile-onset SSc (n = 76) to...
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