Article
ARF1 promotes prostate tumorigenesis via targeting oncogenic MAPK signaling.
Oncotarget - 28 Jun 2016
Davis Jason E, Xie Xiayang, Guo Jianhui, Huang Wei, Chu Wen-Ming, Huang Shuang, Teng Yong, Wu Guangyu
Abstract excerpt
ADP-ribosylation factor 1 (ARF1) is a crucial regulator in vesicle-mediated membrane trafficking and involved in the activation of signaling molecules. However, virtually nothing is known about its function in prostate cancer. Here we have demonstrated that ARF1 expression is significantly elevated in prostate cancer cells and human tissues and that the expression levels of ARF1 correlate with the activation of...
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