G Proteins in Cancer: The Prostate Cancer Paradigm

Abstract excerpt

Signal transduction research investigating mechanisms of androgen-independent prostate cancer cell proliferation has historically focused on the role of androgen and peptide growth factor receptors. More recent work has raised the idea that intracellular signaling mechanisms triggered by extracellular hormonal factors acting through heterotrimeric guanine nucleotide-binding protein (G protein)-coupled receptors...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Hormonal and reproductive studies
• Share to Prostate Cancer Treatment and Research
• Share to Receptor Mechanisms and Signaling