Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CRISPR/Cas9-mediated genome editing reveals 30 testis-enriched genes dispensable for male fertility in mice†

14 Jun 2019

Abstract excerpt

More than 1000 genes are predicted to be predominantly expressed in mouse testis, yet many of them remain unstudied in terms of their roles in spermatogenesis and sperm function and their essentiality in male reproduction. Since individually indispensable factors can provide important implications for the diagnosis of genetically related idiopathic male infertility and may serve as candidate targets for the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CRISPR and Genetic Engineering
Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31201419
DOI: 10.1093/biolre/ioz103

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CRISPR/Cas9-mediated genome editing reveals 30 testis-enriched genes dispensable for male fertility in mice†PMID 31201419Read ↗

CRISPR/Cas9-based genome editing in mice uncovers 13 testis- or epididymis-enriched genes individually dispensable for male reproduction†Semantic proximity Read ↗

Genome engineering uncovers 54 evolutionarily conserved and testis-enriched genes that are not required for male fertility in miceSemantic proximity Read ↗

CRISPR/Cas9-mediated genome editing reveals 12 testis-enriched genes dispensable for male fertility in miceSemantic proximity Read ↗

Individual disruption of 12 testis-enriched genes via the CRISPR/Cas9 system does not affect the fertility of male miceSemantic proximity Read ↗

CRISPR/Cas9-mediated genome-edited mice reveal 10 testis-enriched genes are dispensable for male fecunditySemantic proximity Read ↗

CRISPR/Cas9-Mediated Genome Editing Reveals Oosp Family Genes are Dispensable for Female Fertility in Mice.Semantic proximity Read ↗

Large-scale discovery of male reproductive tract-specific genes through analysis of RNA-seq datasetsSemantic proximity Read ↗

The testis-specific serine proteases PRSS44, PRSS46, and PRSS54 are dispensable for male mouse fertility†Semantic proximity Read ↗

[Mutant generation of the testis genes and phenotype analyses in Drosophila].Semantic proximity Read ↗

Deconstructing mammalian reproduction: using knockouts to define fertility pathwaysSemantic proximity Read ↗

A framework for high-resolution phenotyping of candidate male infertility mutants: from human to mouse.Semantic proximity Read ↗

FertilityOnline, a straight pipeline for functional gene annotation and disease mutation discovery, identifies novel infertility causative mutations in <i>SYCE1</i> and <i>STAG3</i>Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.