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Article

A class of their own: exploring the nondeacetylase roles of class IIa HDACs in cardiovascular disease

23 May 2016

Abstract excerpt

Histone deacetylases (HDACs) play integral roles in many cardiovascular biological processes ranging from transcriptional and translational regulation to protein stabilization and localization. There are 18 known HDACs categorized into 4 classes that can differ on the basis of substrate targets, subcellular localization, and regulatory binding partners. HDACs are classically known for their ability to remove...

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Identifiers

PMID: 27208161
DOI: 10.1152/ajpheart.00271.2016

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