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Article

Patterns of expression of factor VIII and von Willebrand factor by endothelial cell subsets in vivo

13 May 2016

Abstract excerpt

UNLABELLED: Circulating factor VIII (FVIII) is derived from liver and from extrahepatic sources probably of endothelial origin, but the vascular sites of FVIII production remain unclear. Among organs profiled, only liver and lymph nodes (LNs) show abundant expression of F8 messenger RNA (mRNA). Transcriptomic profiling of subsets of stromal cells, including endothelial cells (ECs) from mouse LNs and other...

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PMID: 27207787
DOI: 10.1182/blood-2015-12-684688

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