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Article

Membranous CD24 drives the epithelial phenotype of pancreatic cancer.

Oncotarget - 2 Aug 2016

Lubeseder-Martellato Clara, Hidalgo-Sastre Ana, Hartmann Carolin, Alexandrow Katharina, Kamyabi-Moghaddam Zahra, Sipos Bence, Wirth Matthias, Neff Florian, Reichert Maximilian, Heid Irina, Schneider Günter, Braren Rickmer, Schmid Roland M, Siveke Jens T

Abstract excerpt

Surface CD24 has previously been described, together with CD44 and ESA, for the characterization of putative cancer stem cells in pancreatic ductal adenocarcinoma (PDAC), the most fatal of all solid tumors. CD24 has a variety of biological functions including the regulation of invasiveness and cell proliferation, depending on the tumor entity and subcellular localization. Genetically engineered mouse models...

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Share to Carcinoma, Pancreatic Ductal
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epithelial-Mesenchymal Transition

Share to Epithelium

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Identifiers

PMID: 27203385
DOI: 10.18632/oncotarget.9402
PMCID: PMC5226498

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