Article
High HIV-1 Diversity and Prevalence of Transmitted Drug Resistance Among Antiretroviral-Naive HIV-Infected Pregnant Women from Rio de Janeiro, Brazil.
AIDS research and human retroviruses - 1 Jan 2017
Delatorre Edson, Silva-de-Jesus Carlos, Couto-Fernandez José Carlos, Pilotto Jose H, Morgado Mariza G
Abstract excerpt
Antiretroviral (ARV) resistance mutations in human immunodeficiency virus type 1 (HIV-1) infection may reduce the efficacy of prophylactic therapy to prevent mother-to-child transmission (PMTCT) and future treatment options. This study evaluated the diversity and the prevalence of transmitted drug resistance (TDR) in protease (PR) and reverse transcriptase (RT) regions of HIV-1 pol gene among 87 ARV-naive...
Topics
- Adolescent
- Adult
- Anti-HIV Agents
- Brazil
- Drug Resistance, Viral
- Female
- Genetic Variation
- Genotype
- HIV Infections
- HIV Protease
- HIV Reverse Transcriptase